Our high quality bioanalytical services using the powerful technique of Surface Plasmon Resonance (SPR) provides label-free, real time analysis of any pair of interacting molecules including small molecule drugs binding to their target proteins.

In more than 10 years Biaffin acquired expert knowledge in application of SPR technology  and has proven to be a reliable partner for clients from pharmaceutical and diagnostic industry as well as from academic institutes supporting their specific research projects. 

Our large equipment including a number of different SPR biosensors (Biacore T100, 2x Biacore S51, Biacore 3000, 2x Biacore 2000, Biacore X) ensures a rapid and individual analysis of your samples optimized according to your specific needs.

Our advantages are:

• Strong expertise and knowledge in SPR technology to kinetically characterize any pair of interacting molecules
• Sufficient capacities of Biacore instruments (x7) to perform a number of projects in parallel and to obtain results in time
• Know-how in selection and validation of antibodies based on antigen and Fc receptor binding kinetics
• Determination of active concentrations using SPR-based calibration-free methods
• High sensitivity for analyzing even small molecules binding to immobilized target proteins with special expertise for protein kinases

• Kinetic & affinity measurements (proteins, peptides, DNA, RNA, membranes)
• Drug screening & lead optimization
• Pre-clinical characterization of therapeutic antibodies
• Immunoreactivity & Immunogenicity
• Pharmacokinetics & ADME

All our services include work plans for stepwise assay development with flexible strategies especially suited to achieve your aims.