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Publikationen

Brown KM, Day JP, Huston E, Zimmermann B, Hampel K, Christian F, Romano D, Terhzaz S, Lee LC, Willis MJ, Morton DB, Beavo JA, Shimizu-Albergine M, Davies SA, Kolch W, Houslay MD, Baillie GS (2013) "Phosphodiesterase-8A binds to and regulates Raf-1 kinase." Proc Natl Acad Sci U S A. 2013 Mar 18
Kummer L, Parizek P, Rube P, Millgramm B, Prinz A, Mittl PR, Kaufholz M, Zimmermann B, Herberg FW, Plückthun A. (2012) "Structural and functional analysis of phosphorylation-specific binders of the kinase ERK" Proc Natl Acad Sci USA 2012 Jul 27
Munari F, Soeroes S, Zenn HM, Schomburg A, Kost N, Schroeder S, Klingberg R, Rezaei-Ghaleh N, Stuetzer A, Gelato KA, Walla PJ, Becker S, Schwarzer D, Zimmermann B, Fischle W, Zweckstetter M. "Methylation of K9 in histone H3 directs alternative modes of highly dynamic interaction of heterochromatin protein hHP1beta with the nucleosome" (2012) J Biol Chem. 2012 Jul 19
Grancha S, Ortiz AM, Maranon C, Hampel K, Moret A, Zimmermann B, Jorquera JI, Aznar JA (2012) "Kinetics of the interaction between anti-FVIII antibodies and FVIII from therapeutic concentrates, with and without von Willebrand factor, assessed by surface plasmon resonance" Haemophilia, May 30, 2012
Düvel J, Bertinetti D, Möller S, Schwede F, Morr M, Wissing J, Radamm L, Zimmermann B, Genieser HG, Jänsch L, Herberg FW, Häussler S (2011) "A chemical proteomics approach to identify c-di-GMP binding proteins in Pseudomonas aeruginosa." J Microbiol Methods
Schmidt J, Müsken M, Becker T, Magnowska Z, Bertinetti D, Möller S, Zimmermann B, Herberg FW, Jänsch L, Häussler S (2011) "The Pseudomonas aeruginosa Chemotaxis Methyltransferase CheR1 Impacts on Bacterial Surface Sampling" PLoS One 6, 3
Christian F, Szaszak M, Drewianka S, Hampel K, Herberg FW, Zimmermann B, Rosenthal W, Klussmann E (2011) "Small molecule AKAP/PKA interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes" J Biol Chem. 2011 Jan 5.
Fender A, Elf J, Hampel K, Zimmermann B, Wagner EG (2010) "RNAs actively cycle on the Sm-like protein Hfq" Genes Dev. 24(23):2621-6
Lorenz U, Lorenz B, Schmitter T, Streker K, Erck C, Wehland J, Nickel J, Zimmermann B, Ohlsen K. (2010) "Functional antibodies targeting IsaA of Staphylococcus aureus augment host immune response and open new perspectives for antibacterial therapy" Antimicrob Agents Chemother. 2010 Oct 18
Diskar M, Zenn HM, Kaupisch A, Kaufholz M, Brockmeyer S, Sohmen D, Berrera M, Zaccolo M, Boshart M, Herberg FW , Prinz A. (2010) Regulation of cAMP-dependent protein kinases: the human Protein Kinase X (PrKX) reveals the role of the catalytic subunit alpha H alpha I loop." J Biol Chem. 2010 Sept 6
Hundsrucker C, Skroblin P, Christian F, Zenn HM, Popara V, Joshi M, Eichhorst J, Wiesner B, Herberg FW , Reif B, Rosenthal W, Klussmann E. (2010) "Glycogen synthase kinase 3beta interaction protein functions as an A-kinase anchoring protein." J Biol Chem. 285(8):5507-21
Zenn HM, Hutschenreiter S and Herberg FW (2010) "Anti-Histidine Antibodies as Tools for Reversible Capturing of His-Tagged Fusion Proteins for Subsequent Binding Analysis" Antibody Engineering, Part V: 667-681
Bertinetti D, Schweinsberg S, Hanke SE, Schwede F, Bertinetti O, Drewianka S, Genieser HG, Herberg FW (2009) "Chemical tools selectively target components of the PKA system." BMC Chem Biol. 9:3
Zimmermann B, Schweinsberg S, Drewianka S, Herberg FW (2008) "Effect of metal ions on high-affinity binding of pseudosubstrate inhibitors to PKA." Biochem J. 413(1):93-101
Schweinsberg S, Moll D, Burghardt NC, Hahnefeld C, Schwede F, Zimmermann B, Drewianka S, Werner L, Kleinjung F, Genieser HG, Schuchhardt J, Herberg FW (2008) "Systematic interpretation of cyclic nucleotide binding studies using KinetXBase" Proteomics 8(6):1212-20
Mirow N, Zimmermann B, Maleszka A, Knobl H, Tenderich G, Koerfer R, Herberg FW (2007) "Plasma Protein Binding Properties to Immobilized Heparin and Heparin-Albumin Conjugate" Artif Organs 31(6):466-71
Seitz H, Hutschenreiter S, Hultschig C, Zeilinger C, Zimmermann B, Kleinjung F, Schuchhardt J, Eickhoff H, Herberg FW (2006) "Differential binding studies applying functional protein microarrays and surface plasmon resonance" Proteomics 6(19):5132-9
Gesellchen, F., Prinz, A., Zimmermann B., Herberg F.W. (2006). "Quantification of cAMP antagonist action in vitro and in living cells." Eur J Cell Biol. 85(7):663-72
Hundsrucker C, Krause G, Zimmermann B, Diekmann O, Herberg FW, Scott JD, Rosenthal W, Klussmann E et al. (2006) "High-affinity AKAP7delta-protein kinase A interaction yields novel protein kinase A-anchoring disruptor peptides" Biochem J. 396(2):297-306
Moll D., Zimmermann B., Gesellchen F., Herberg F.W. (2006) “Current developments for the in vitro characterization of protein interactions”. Proteomics in Drug Research. Edit. by K. Marcus, K. Stühler, Warscheidet et al. Weinheim, Wiley-VCH
Moll D., Prinz A., Gesellchen F., Drewianka S., Zimmermann B. and Herberg F.W. (2006) "Biomolecular interaction analysis in functional proteomics" J. Neural Transmission
Gesellchen F., Zimmermann B., and Herberg F.W. (2005) "Direct Optical Detection of Protein–Ligand Interactions" Humana Press, Methods in Molecular Biology, Protein–Ligand Interactions: Methods and Applications, Vol. 305, chapter 2, 17-46
Ramanavicius A., Herberg F.W. et al. (2005). "Biomedical Application of Surface Plasmon Resonance Biosensors" Acta Medica Lithuania 12 (3): 1–9
Schaumburg J, Diekmann O, Karst U et al. (2004) "The cell wall subproteome of Listeria monocytogenes" Proteomics. 2004 Oct;4(10):2991-3006
Thierse H.J., Moulon C., Allespach Y., Zimmermann B., Doetze A., Kuppig S., Wild D., Herberg F., Weltzien H.U. (2004) “Metal-protein complex-mediated transport and delivery of Ni2+ to TCR/MHC contact sites in nickel-specific human T cell activation” J Immunol. 172(3):1926-34
Hahnefeld C., Drewianka S., Herberg F.W. (2004) “Determination of kinetic data using surface plasmon resonance biosensors” Methods Mol Med. 94:299-320
Yaqub S., Abrahamsen H., Zimmermann B., Kholod N., Torgersen K.M., Mustelin T., Herberg F.W., Tasken K., Vang T. (2003) “Activation of c-terminal Src kinase (Csk) by phosphorylation at Ser-364 depends on the Csk SH3 domain”, Biochem. J. 372, 271-278
Bergmann S, Wild D, Diekmann O, Frank R, Bracht D, Chhatwal GS, Hammerschmidt S.(2003) “Identification of a novel plasmin(ogen)-binding motif in surface displayed alpha-enolase of Streptococcus pneumoniae”, Mol Microbiol. 49(2):411-23
Zimmermann B., Hahnefeld C., Herberg F.W. (2002) “Applications of biomolecular interaction analysis in drug development”, Targets 2 (1) 66-73
Gioia M, Fasciglione GF, Marini S, D'Alessio S, De Sanctis G, Diekmann O, Pieper M, Politi V, Tschesche H, Coletta M. (2002) “Modulation of the catalytic activity of neutrophil collagenase MMP-8 on bovine collagen I. Role of the activation cleavage and of the hemopexin-like domain”, J Biol Chem., 277(26):23123-30
Wang X., Hu B., Zimmermann B., Kilimann M.W. (2001) “Rim1 and Rabphilin-3 bind Rab3-GTP by composite determinants partially related through N-terminal alpha-helix motifs”, J. Biol. Chem. 276 (35), 32480-8
Kemminer SE, Conradt HS, Nimtz M, Sagi D, Peter-Katalinic J, Diekmann O, Drmic I, Muthing J. (2001) “Production and molecular characterization of clinical phase i anti-melanoma mouse IgG3 monoclonal antibody R24”, Biotechnol Prog., 17(5):809-21
Herberg F.W. & Zimmermann B. (1999) “Analysis of protein kinase interactions using biomolecular interaction analysis”, Protein Phosphorylation, A Practical Approach, edited by D.G. Hardie, Oxford University Press
Zimmermann B., Chiorini J.A., Kotin R.M., Herberg F.W. (1999) “PrKX is a novel catalytic subunit of the cAMP-dependent protein kinase regulated by the regulatory subunit type I”, J. Biol.Chem. 274, 9, 5370-5378
Herberg F.W., Doyle M.L., Cox S., Taylor S.S. (1999), “Dissection of the nucleotide and metal-phosphate binding sites in cAMP-dependent protein
kinase”, Biochemistry 38(19):6352-60
Gehrmann T., Gulkan H., Suer S., Herberg F.W., Balla A., Vereb G., Mayr G.W., Heilmeyer L.M. Jr (1999), “Functional expression and characterisation of a new human phosphatidylinositol 4-kinase PI4K230”, Biochim. Biophys. Acta 1437(3):341-56
Schliebs W., Saidowsky J., Agianian B., Dodt G., Herberg F.W., Kunau W.H. (1999), “Recombinant human peroxisomal targeting signal receptor PEX5. Structural basis for interaction of PEX5 with PEX14”, J. Biol. Chem. 274(9):5666-73
Zimmermann B. & Herberg F.W. (1998) “Interactions of 6xHis-tagged protein kinase A catalytic subunit examined using Ni-NTA Magnetic agarose beads”, QIAGEN News 4/98, 9-10
Chiorini J.A., Zimmermann B., Yang L., Smith R.H., Ahearn A., Herberg F.W., Kotin R.M. (1998) “Inhibition of PrKX, a novel protein kinase, and the cAMP-dependent protein kinase PKA, by the regulatory proteins of Adeno-associated virus type 2”, Mol. Cell. Biol. 18: 5921-5929
Reiffert S.U., Jaquet K., Heilmeyer L.M.G. jr, Herberg F.W. (1998), “Stepwise Subunit Interaction Changes by Mono- and Bisphosphorylation of Cardiac Troponin I”, Biochemistry 37 (39), 13516-13525 (1998)
Orth T, Kellner R, Diekmann O, Faust J, Meyer zum Buschenfelde KH, Mayet WJ. (1998), “Identification and characterization of autoantibodies against catalase and alpha-enolase in patients with primary sclerosing cholangitis”, Clin Exp Immunol., 112(3):507-15
Jaeger W., Haase B., Lutz V., Herberg F.W. and Zimmermann B. (1997) “Biomolekulare Interaktionsanalyse (BIA) mit SPR-Biosensortechnologie”, Biospektrum 3(4), 8-87
Herberg F.W., Zimmermann B., McGlone M., Taylor S.S. (1997) “Importance of the A-helix of the catalytic subunit of cAMP-dependent protein kinase for stability and for orienting subdomains at the cleft interface”, Protein Science 6, 569-79
Billinghurst RC, Dahlberg L, Ionescu M, Reiner A, Bourne R, Rorabeck C, Mitchell P, Hambor J, Diekmann O, Tschesche H, Chen J, Van Wart H, Poole AR. (1997), “Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage”, J Clin Invest., 99(7):1534-45
Herberg F.W., Taylor S.S., Dostmann W.R. (1996), “Active site mutations define the pathway for the cooperative activation of cAMP-dependent protein kinase”, Biochemistry 35(9), 2934-2942
Wild N., Herberg F.W., Hofmann F., Dostmann W.R. (1995), “Expression of a chimeric, cGMP-sensitive regulatory subunit of the cAMP-dependent protein kinase type I alpha”, FEBS Lett. 374(3), 356-362
Su Y., Dostmann W.R., Herberg F.W., Durick K., Xuong N.H., Ten Eyck L., Taylor S.S., Varughese K.I. (1995) “Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains”, Science 269(5225), 807-813
Herberg F.W., Dostmann W.R., Zorn M., Davis S.J., Taylor S.S. (1994) “Crosstalk between domains in the regulatory subunit of cAMP-dependent protein kinase: influence of amino terminus on cAMP binding and holoenzyme formation”, Biochemistry 33(23), 7485-7494
Diekmann O, Tschesche H. (1994), “Degradation of kinins, angiotensins and substance P by polymorphonuclear matrix metalloproteinases MMP 8 and MMP 9”, Braz J Med Biol Res., 27(8):1865-76
Herberg F.W., Taylor S.S. (1993), “Physiological inhibitors of the catalytic subunit of cAMP-dependent protein kinase: effect of MgATP on protein-protein interactions”, Biochemistry 32(50), 14015-14022 (1993)
Herberg F.W., Bell S.M., Taylor S.S. (1993) “Expression of the catalytic subunit of cAMP-dependent protein kinase in Escherichia coli: multiple isozymes reflect different phosphorylation states”, Protein Eng. 6(7), 771-777