About Us

COMPANY PROFILE

Biaffin is a leading provider of high quality bioanalytical services and contract research specialising in biomolecular interaction analysis (BIA) for customers from the pharmaceutical, biotechnological and diagnostic industry.

Biaffin has acquired long experience and expert knowledge in the application of real-time biosensors based on surface plasmon resonance (SPR) and is known to be a reliable partner for the performance of biomolecular interaction analyses. Furthermore, Biaffins service features comprise in vitro kinase activity assays using the microfluidic mobility-shift approach as well as photometric and bioluminescent based methods. Proteinkinase.de, the distribution platform of Biaffin, functions as a specialized supplier of kinase related products.

FIELDS OF BUSINESS ACTIVITY

Biomolecular affinity analysis with biosensors

scientific service and contract research
development of novel biological sensor surfaces
consulting and concept development

Unique selling point(s)

methods for specific immobilisation of biomolecules on sensor surfaces
new ligand surfaces (e.g. on the basis of nucleotide derivates)
effects of protein phosphorylation

Selected further services

protein expression and purification
kinetic analyses of kinase properties (kinase activity assays)

SERVICE

BIA technology is employed in various stages of the drug development process like target validation, secondary screening, hit validation and assay development. Biacore instruments are applied in functional assays, in kinetic characterisation of antibodies for diagnostic purposes as well as in quality control of recombinant proteins and in the development of biocompatible surfaces.

Our services include assay development for medium to high throughput binding assays and consulting for the development of novel sensor technologies with emphasis on biological applications.
We also provide screening of kinase activity by the Caliper’s mobility shift assay technology, allowing an in-depth analysis of enzyme kinetics, kinase inhibitor profiling or substrate specification.

PRODUCTS

Biaffin´s products are recombinant proteins such as protein kinases and phosphatases, cytokines, kinase inhibitors, substrates, activators of signaling pathways, antibodies as well as bioluminescence-based assays for ATP quantification. If you are interested in our range of products please take a look at our distribution platform proteinkinase.de.